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Answer to: role of spores in the development of c. difficile disease
C. difficile is transmitted from person to person by the fecal – oral route . The organism forms heat – resistant spores that are not killed by alcohol – based hand cleansers or routine surface cleaning . Thus , these spores survive in clinical environments for long periods . Because of this , the bacteria may be cultured from almost any surface . Once spores are ingested , their acid – resistance allows them to pass through the stomach unscathed . Upon exposure to bile acids , they germinate and multiply into vegetative cells in the colon .
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role of spores in the development of c. difficile disease
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